Cell-cell contact affects cellular sensitivity to hyperthermia
نویسندگان
چکیده
منابع مشابه
Cell to cell interactions influence sensitivity of liver cell lines during hyperthermia.
BACKGROUND Thermal cancer therapy is used for hepatocellular carcinoma treatment. In this study we investigated the effect of hyperthermia on liver cells and compared data of our different cell culture fibrosis models (transwell vs. co-culture model). MATERIALS AND METHODS The cell lines HepG2 and LX-1 were seeded in different numbers in transwells to simulate different grades of fibrosis and...
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Vol. 30, No. 1, 2018 107 Received November 1, 2016, Revised December 29, 2016, Accepted for publication January 26, 2017 Corresponding author: Yan Wu, Department of Dermatology, No. 1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China. Tel: 86-24-83282116, Fax: 86-24-83282633, E-mail: [email protected] Xinghua Gao, Department of Dermatology, No. 1 Hospital of C...
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Background: Although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. Objective: To investigate natural killer (NK) cell cytotoxicity against heat-treated SW-872 and HeLa tumor cell lines. Methods: NKG2D ligands and HLA class I transcription were examin...
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The weight ratio of either cholesterol or phospholipid to protein contents in 7 different cell lines, growing exponentially at 37°, correlates positively with increasing resistance of the cells to subsequent hyperthermic cell killing. The relative heat resistance of each cell line is derived from survival curves obtained when the different cell lines are exposed to 43°. Cholesterol and phosph...
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The weight ratio of either cholesterol or phospholipid to protein contents in 7 different cell lines, growing exponentially at 37 degrees, correlates positively with increasing resistance of the cells to subsequent hyperthermic cell killing. The relative heat resistance of each cell line is derived from survival curves obtained when the different cell lines are exposed to 43 degrees. Cholestero...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1985
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1985.268